The shills at Medical News Today recently posted an article based on a new study performed on mice, which should say all you need to know — as mice react differently to various toxins, have a completely different anatomy and organ proportions, have a different metabolic profile, including a different nutrient uptake, processing, and storage.
With that said, the study looked at mice with “cancer” and what happened during a refeeding period after fasting for 24 hours.
MNT begins their article with Intermittent Fasting, which is totally irrelevant to this study, so let’s skip to the relevant parts.
“Now, a study led by researchers from MIT has found out how fasting and then refeeding stimulates cell regeneration in the intestines but has also shown that it carries the risk of stimulating the formation of intestinal tumors. The study, which was carried out in mice, is published in Nature.”
As you should know, tumors are either the result of your body protecting you by shielding off toxic build-up into these protective tissues, or by forming new cells to better deal with high blood glucose levels in people who over consume carbohydrates, or from repeated mental trauma.
As for intestinal tumors, especially in the colon, it’s usually from a combination of toxic buildup and repeated damage from consuming plant-based (mainly fiber, defense chemicals, and antinutrients) and processed foods. I’ve covered cancer in depth in several articles, just follow the links to get up to speed.
New findings on the benefits of fasting
“Previous studies from the same research group have shown that mice that are fasted for 24 hours, then fed their normal diet have enhanced intestinal stem cell function, which may promote intestinal regeneration and aid recovery from injuries or inflammation.”
Of course, when you do not eat, you do not tax the digestive system and it finally has some time to heal and recover from any damage you have accumulated. After about 8 to 16 hours, autophagy is engaged, where your body breaks down and recycles damaged cells. This recycling provides building blocks for new cells. Once you start eating again and get some extra nutrients from an outside source, autophagy is turned off as your body has to deal with the exogenous nutrients. However, the healing response, as in tissue repair, is temporarily magnified for a short period of time due to the onslaught of nutrients.
“In this study, researchers divided the mice into three groups: group one fasted for 24 hours; group 2 fasted for 24 hours and then was allowed to eat whatever they wanted during a 24-hour refeeding period; and a control group ate whatever they wanted throughout the experiment. All groups had unlimited access to water at all times.”
Actually, according to the authors of the study, mice in both fasting groups were deprived of food for 24 hours; mice in group 1 had free access to food following a 24 h fast for 1 day (Refed 1d,) and group 2 had free access to food for 3 days (Refed 3d.)
And this is a significant mistake by the researchers. No one who practices fasting will eat whatever and how much they want for a day, much less for three days after fasting. Any one who practices fasting breaks their fast gently with a small and easily digestible meal, like meat, fish, or eggs, and then they resume their normal eating pattern. They do not eat whatever or as much as they want.
As for the mice, they were fed a standard laboratory diet; as in a commercial pellet rodent chow that is very high in carbohydrate sources that are not found in their natural diet, has mainly plant-based protein sources (mice should eat a lot of insects, bugs, and small animals,) and has a shitload of added toxic synthetic vitamins, “antioxidants,” preservatives, and sterilization agents nowhere to be found in nature. Also, the fat comes from seed/vegetable oils, which means that they are rancid and destroyed, as they are extremely sensitive to oxygen and light. All seed/vegetable fats, as in unsaturated fats, are rancid the moment they are processed and extracted from the source.
So, the mice were allowed to overindulge in toxic food for either 24 hours or a horrifying 72 hours. What could possibly go wrong?
What they should have done, to at least get some interesting data, would be to put the mice on a controlled and scheduled and natural diet to maintain their weight for a few weeks, then fasted them for 24 hours, and then have one group simply resume their normal feeding schedule while a second group was allowed to eat how much they wanted for either 24 or 48 hours.
“They found that the stem cells’ ability to multiply was highest during the 24-hour refeeding period in mice that had previously fasted for 24 hours. These cells also replicated more rapidly than intestinal stem cells from mice that had not fasted at all.”
Yes, I described this earlier. Cell breakdown and recycling is shut down, while the repair process gets an extra boost from more available nutrients. Even if the pellets given to the mice are extremely toxic, there is still plenty of nutrients that they can extract.
“The cells also activated a cellular signaling pathway, called mTOR, that is involved in cell metabolism, growth, and regulating protein synthesis. When it is activated, cells produce more protein, which is vital for proliferation of stem cells.”
Yes, although mTOR can be activated through multiple pathways, the most common are through an abundance of nutrients, especially amino acids and leucine, and through insulin and insulin-like growth factor 1 (IGF-1) signaling, which is also an effect of more nutrients in the bloodstream.
“The researchers demonstrated that when mTOR is activated in these stem cells, they produce higher levels of polyamines — small molecules needed for cell growth and division.”
What you describe as “cell division,” specifically mitosis, is something that happens continuously throughout an organism’s life to replace damaged and dying cells (upregulated during autophagy,) to regenerate skin, blood and epithelial cells, and to support growth and development.
And yes, polyamines are small polycations derived from the amino acids arginine and/or ornithine. They are ubiquitous intracellular cationic amines, present in all living organisms where they facilitate cell growth and development through various cellular responses.
“Evolutionarily this would make sense – after a difficult time or a period without resources, the body would prioritize cell regeneration as soon as it got food or resources again. It does not know when the next hardship is going to come, so it needs to repair and prepare the cells for the next difficult period.”
Well, it’s much simpler than that. You are not meant to eat several times a day, as you can do in this inverted modern society of overabundance. You are meant to only have one or two meals a day, and to go without food for a day or more every now and then. That is what your body is designed for and how it detoxes, heals, and repairs accumulated damage. You can only detox and recycle damaged cells in a fasted state, as in at least 6 to 8 hours without food.
Whenever you eat something, all these pathways are shut down as your body has to prioritize digestion and taking care of the nutrients, or worse, your blood glucose, if you’re so dumb that you consumed carbohydrates.
To conclude, being deprived of food for various lengths are natural and what our physiology is built for, and that is how we regenerate and stay young and healthy. And this is why smart people have their last meal at least 4 to 6 hours before bed, so the digestive system can relax and you enter a fasted state during sleep to facilitate detoxing and healing.
What are the negative effects of fasting?
There are none if you’re fully nourished. However, if you’re malnourished, as in following a plant-based diet or worse (extremely retarded vegan/fruitarian diets,) you will do great damage as you will actually be starving and breaking down essential tissues to help with the nutrient deficiencies, and if malnourished, most processes in the body will be compromised, as there is not enough nutrients available for them to work. That will result in hormone imbalances, poor enzymatic reactions, and so on. For more, read my articles on fasting.
“According to the National Cancer Institute: Cancer is a disease in which some of the body’s cells grow uncontrollably and spread to other parts of the body. So could cells that are prompted to proliferate lead to cancers?”
No, cancer is nothing of that sort. That is pseudoscience put forth by the medical- and pharmaceutical industry. Cancer, as in developing tumors, is a bodily defense against toxemia and/or repeatedly elevated blood glucose. The “cancer” in itself is your best friend, as it gives you a chance to change your lifestyle or you would already be dead from the high toxic load. It’s what is causing the body to take this measure of forming tumors that is the enemy, as in toxins and carbohydrates. Please read my articles on cancer to keep up with the real science, as covered by those who actually understand physiology, biology, and microbiology, and are not chilling for the elite families, their Big Pharma and food industry.
“When the researchers turned on a cancer-causing gene in the mice during refeeding, the cells were much more likely to develop into precancerous polyps than if the gene was turned on during fasting.”
Again, that is not how cancer works. In short, what these researchers do is pick out a component from a cell culture that they think is a “gene,” which they modify to create a mutated or overexpressed version. They insert it into a plasmid to deliver it to a mouse embryo. These modified embryos are then surgically implanted into a pseudopregnant female mouse (as in toxic hormone therapy.) They then screen the offspring for abnormalities, and those who got poisoned by the modified cell culture are selected for further study. Then they think that they can “activate” this “gene” in the offspring by administering certain Cre Recombinase compounds and Tetracycline-inducible systems. In other words, they inject the offspring with a myriad of toxic crap causing acute poisoning. Yes, it’s pseudo science.
So, we have “modified mice,” as in severely damaged offspring that will react differently to stimulus compared to healthy mice, likely by impaired ability to detox which will make them develop “cancer,” as in protective tumors, a lot quicker than other mice. And to activate what the scientists believe is this “cancer gene” they severely poison the mice. No wonder that they might develop precancerous polyps as a result during a toxic all-you-can-eat refeed — as this toxic food has an acute impact on the digestive system, and especially the colon.
And as a note, precancerous polyps are abnormal growths on the lining of the colon or rectum, which is usually the result of both damage and toxic build-up from an unhealthy diet. For humans, that is often the result of consuming fiber and plant-based foods that contain defense chemicals and antinutrients, as well as processed foods with a lot of toxic chemicals and seed/vegetable oils.
“The authors cautioned that, although these results were in mice, it is possible that if you were to eat a mutagenic food — a food at risk of causing mutations — such as a piece of charred meat soon after fasting, you might increase the chance of developing a cancerous lesion.”
So, now you admit that toxic foods can cause “mutations” as in tumors — that it is actually toxins that cause tumors and not an “uncontrollable” cell growth. Interesting. And no-one should ever consume “charred meat.” Like, who does that? Any meat cooked more than rare is a sacrilege. Seriously though, even cooked meat as in ‘well-done’ is totally harmless, just less nutritious due to the cooking. Only burnt and charred meat can be toxic. But you have to be pretty stupid to eat that, especially after fasting.
And with that said, we know that animal-based foods, such as meat, are the only foods that have ZERO toxins in them (unless burnt, of course.) Only plant-based foods are full of toxins. Some vegetables, nuts, and seeds can have several hundred different defense chemicals and antinutrients, and each and everyone attacks different cells.
Should you try fasting or not?
“Fasting regimens, especially those lasting 24 hours or more, have been shown to enhance metabolic health and promote tissue regeneration across various species, including some research in humans. This practice may reverse age-related declines in stem cell function, rejuvenating both blood-forming and intestinal stem cells.
In people, she added, fasting regimens may decrease calorie intake, body weight, body fat, blood pressure, triglycerides, blood glucose, glucose intolerance, and inflammatory markers, supporting a healthy metabolism and helping to prevent or treat chronic conditions like obesity and type 2 diabetes.”
Yes, we all know this, and much more. We are physiologically designed to go through the occasional period of fasting.
“However, she cautioned:
This study also suggests that while fasting and calorie restriction may prevent or slow tumor growth, the period of eating after fasting, known as refeeding, might increase the risk of developing tumors if exposed to carcinogens or genetic changes (mutations) occur during this time.”
Likely not, unless you glutton like a pig on plant-based and/or processed food and already have extreme damage and toxic build-up in your colon.
However, even if this could happen during the first hours of refeeding, if you use common sense and break your fast gently and then resume your normal regular eating habits, you’ll be perfectly fine. Also, during the time you fast, if you have damage and toxic build-ups in your colon, that will be remedied every time you fast until you’re fully healed. So, even if this could happen if you went full retard like the poor mice after fasting, the question is if the refeed did more damage than the fasting healed for you. While it appears so in the mice that were poisoned to “trigger a gene” and then allowed to pig out for 24 to 72 hours on extremely toxic food, it’s unlikely to happen to a human who only has some damage and a bit of toxemia.
To conclude, do not buy into the silly fear mongering put forth by medical- and pharmaceutical interests. They want you sick, so they can profit from you. All you need is some logic and common sense. Humans are carnivores and were built for going without food every now and then. Simply looking at our physiology makes that undeniable.
If you need help with your health, nutrition, and/or transitioning from your current way of eating to our natural species-appropriate, species-specific way of eating, I’m available for both coaching and consultation.
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